111495-86-4 , 2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-glucopyranoside

Cas:111495-86-4 ,
2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-glucopyranoside
C12H13FN2O9 / 348.24
MFCD00132931

2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-glucopyranoside

2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-glucopyranoside is a fluorinated derivative of 2,4-dinitrophenyl 2,3,5,6 tetrafluorobenzoyl bromide. It is an inhibitor of the enzyme complex cGMP phosphodiesterase (PDE), which is involved in the regulation of blood pressure and heart rate. This compound also has been shown to inhibit the production of inflammatory cytokines by polymorphonuclear leucocytes. Clinical relevance studies have demonstrated that 2,4-Dinitrophenyl 2-deoxy-2-fluoro-b-D-glucopyranoside may be a potential treatment for metastatic colorectal cancer.

CAS Number	111495-86-4
Product Name	2,4-Dinitrophenyl 2-Deoxy-2-Fluoro-Beta-D-Glucopyranoside
IUPAC Name	6-(2,4-dinitrophenoxy)-5-fluoro-2-(hydroxymethyl)oxane-3,4-diol
Molecular Formula	C12H13FN2O9
Molecular Weight	348.24 g/mol
InChI	InChI=1S/C12H13FN2O9/c13-9-11(18)10(17)8(4-16)24-12(9)23-7-2-1-5(14(19)20)3-6(7)15(21)22/h1-3,8-12,16-18H,4H2
InChI Key	UFSBFVZQJZMIOU-LZQZFOIKSA-N
SMILES	C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)F
Canonical SMILES	C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])OC2C(C(C(C(O2)CO)O)O)F
Isomeric SMILES	C1=CC(=C(C=C1[N+](=O)[O-])[N+](=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)CO)O)O)F