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37266-93-6 , Sucrose dodecanoate

37266-93-6 , Sucrose dodecanoate ;
b-​D-​Fructofuranosyl-a-​D-​glucopyranoside dodecanoate; Sucrose laurate; (2S,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)tetrahydro-2-furanyl]-3,4,5-trihydroxy-6-(hydroxymethyl)tetrah ydro-2H-pyran-2-yl laurate,
Cas:37266-93-6
C24H44O12 / 524.60

Sucrose dodecanoate

蔗糖月桂酸酯,

b-D-Fructofuranosyl-a-D-glucopyranoside dodecanoate; Sucrose laurate; (2S,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-Dihydroxy-2,5-bis(hydroxymethyl)tetrahydro-2-furanyl]-3,4,5-trihydroxy-6-(hydroxymethyl)tetrah ydro-2H-pyran-2-yl laurate

Sucrose dodecanoate is a sugar ester that has been shown to be a 5-HT agonist. It is used as an absorption enhancer for the treatment of choroidal neovascularization. Sucrose dodecanoate was also found to have trypsin-like protease activity and cyclic peptide properties. This drug has been shown to increase insulin sensitivity and growth factor levels in animal models, which may be due to its effects on serine proteases. Sucrose dodecanoate is available as a pharmaceutical dosage form containing fatty acid esters at a concentration of 10%. It has a viscosity of approximately 100 cP, which is expected to provide good bioavailability.

CAS Number37266-93-6
Product Namealpha-D-Glucopyranoside, beta-D-fructofuranosyl, dodecanoate
IUPAC Name(2R,3R,4S,5S,6R)-2-[(2S,3S,4S,5R)-3,4-dihydroxy-2,5-bis(hydroxymethyl)oxolan-2-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol;dodecanoic acid
Molecular FormulaC24H44O12
Molecular Weight524.60 g/mol
InChIInChI=1S/C12H22O11.C12H24O2/c13-1-4-6(16)8(18)9(19)11(21-4)23-12(3-15)10(20)7(17)5(2-14)22-12;1-2-3-4-5-6-7-8-9-10-11-12(13)14/h4-11,13-20H,1-3H2;2-11H2,1H3,(H,13,14)/t4-,5-,6-,7-,8+,9-,10+,11-,12+;/m1./s1
InChI KeyPVVVEHXCVQRLOC-AKSHDPDZSA-N
SMILESCCCCCCCCCCCC(=O)O.C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O
Synonymslauryl sucrose
Canonical SMILESCCCCCCCCCCCC(=O)O.C(C1C(C(C(C(O1)OC2(C(C(C(O2)CO)O)O)CO)O)O)O)O
Isomeric SMILESCCCCCCCCCCCC(=O)O.C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O[C@]2([C@H]([C@@H]([C@H](O2)CO)O)O)CO)O)O)O)O


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