4990-81-2, 6-Chloro-6-deoxy-D-mannose, CAS:4990-81-2

4990-81-2 , 6-Chloro-6-deoxy-D-mannose,
CAS:4990-81-2
C6H11ClO5 / 198.60
MFCD00671701

6-氯-D-甘露糖, 6-Chloro-D-mannose

6-Chloro-6-deoxy-D-mannose

CAS No: 4990-81-2 MDL No: MFCD00671701 Chemical Formula: C6H11ClO5 Molecular Weight: 198.60

6-Chloro-6-deoxy-D-mannose is a naturally occurring sugar that is found in the spermatozoa of many animals. It is a mannose derivative that has been shown to be an inhibitor of the enzyme glyceraldehyde 3-phosphate dehydrogenase, which plays an important role in energy metabolism and isomerization of 6-phosphate to glucose-1 phosphate. This property may be responsible for its contraceptive effects. The drug also inhibits phosphoglucomutase and enhances the transfer of glucose from the liver to other tissues, increasing blood glucose concentrations. 6-Chloro-6 deoxy mannose also has antifertility effects in rats by inhibiting transfer of spermatozoa through the female reproductive tract.

CAS Number	4990-81-2
Product Name	(2S,3S,4S,5S)-6-Chloro-2,3,4,5-tetrahydroxyhexanal
IUPAC Name	(2S,3S,4S,5S)-6-chloro-2,3,4,5-tetrahydroxyhexanal
Molecular Formula	C6H11ClO5
Molecular Weight	198.6 g/mol
InChI	InChI=1S/C6H11ClO5/c7-1-3(9)5(11)6(12)4(10)2-8/h2-6,9-12H,1H2/t3-,4-,5-,6-/m1/s1
InChI Key	ZHVNVPHMOCWHHO-UHFFFAOYSA-N
SMILES	C(C(C(C(C(C=O)O)O)O)O)Cl
Synonyms	6-chloro-6-deoxymannose
Canonical SMILES	C(C(C(C(C(C=O)O)O)O)O)Cl

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