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56245-60-4,Ethyl β-D-thiogalactopyranoside, CAS:56245-60-4

56245-60-4,Ethyl β-D-thiogalactopyranoside,
C8H16O5S / 224.28



(2S,3R,4S,5R,6R)-2-(Ethylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is a chemical compound that has been the focus of extensive scientific research over the last few decades. This paper will provide an overview of the definition and background, physical and chemical properties, synthesis and characterization, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, and potential implications in various fields of research and industry. Additionally, the paper will discuss limitations and future directions for research concerning (2S,3R,4S,5R,6R)-2-(Ethylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol.

Definition and Background

(2S,3R,4S,5R,6R)-2-(Ethylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol is a chemical compound that is commonly known as ethylthioglycosides. The compound is classified as a tetrahydropyran glycoside and is frequently used in biological and medicinal chemistry. Ethylthioglycosides are utilized as glycosyl donors in the chemical synthesis of oligosaccharides, which are essential components of cell membranes and play critical roles in biological processes in the human body.

Synthesis and Characterization

The synthesis of ethylthioglycosides can be achieved through various chemical reactions, including glycosylation, silylation, and thiolation. Glycosylation, which involves the reaction of a glycosyl donor with a glycosyl acceptor, is the most common method for synthesizing ethylthioglycosides. Silylation and thiolation are also utilized, but these methods are less commonly used due to the intricacy of the reaction mechanisms and the availability of the necessary reagents.

Analytical Methods

A variety of analytical methods can be used to characterize and analyze ethylthioglycosides, including nuclear magnetic resonance (NMR) spectroscopy, high-performance liquid chromatography (HPLC), and mass spectrometry (MS). These methods are commonly used to identify specific structural features of the ethylthioglycosides, determine purity, and assess the effectiveness of chemical reactions.

Biological Properties

Ethylthioglycosides have demonstrated a wide range of biological properties, including antibacterial, antiviral, antifungal, and anti-inflammatory activities. These properties may be attributed to the compound's ability to disrupt bacterial cell wall formation and inhibit the activity of enzymes involved in viral replication.

Toxicity and Safety in Scientific Experiments

Research has shown that ethylthioglycosides have low toxicity and are generally safe to use in scientific experiments. However, it is recommended that researchers take appropriate safety precautions, such as using personal protective equipment, to minimize any potential hazards associated with handling the compound.

Applications in Scientific Experiments

Ethylthioglycosides have various applications in scientific experiments, including the synthesis of oligosaccharides, glycomics research, and drug discovery. The compound is frequently used as a glycosylation reagent in the formation of complex carbohydrate structures that can be used as antigens, vaccines, and diagnostic tools. In addition, ethylthioglycosides can be utilized in glycomics research to study the role of carbohydrates in biological processes and diseases.

Current State of Research

Recent research has focused on the synthesis of novel ethylthioglycosides with improved properties, such as increased solubility, stability, and bioactivity. Additionally, researchers are exploring the use of ethylthioglycosides in the development of new drugs and therapies for various diseases, including cancer, Alzheimer's disease, and diabetes. The current state of research suggests that ethylthioglycosides represent a promising avenue for further investigation in the fields of biology and medicine.

Potential Implications in Various Fields of Research and Industry

The potential implications of ethylthioglycosides extend beyond biology and medicine. The unique chemical properties of the compound make it a promising candidate for use in the synthesis of novel polymers, catalysis, and materials science. As a result, there is growing interest in the use of ethylthioglycosides in industrial applications, such as the development of biosensors and biomaterials.

Limitations and Future Directions

Despite the potential benefits of ethylthioglycosides, there are limitations to the current research. For example, the synthesis of ethylthioglycosides can often be challenging, and the cost of the reagents required for synthesis may limit their use. Additionally, further research is needed to fully understand the biological mechanisms and potential therapeutic applications of ethylthioglycosides.

Future directions for research include the development of more efficient and cost-effective methods for synthesizing ethylthioglycosides, as well as the exploration of new applications in industry and medicine. Further investigation into the biological properties and therapeutic potential of ethylthioglycosides may lead to the development of novel drugs and therapies for various diseases. Finally, the exploration of the industrial applications of ethylthioglycosides may lead to the development of innovative technologies that can improve our daily lives.

CAS Number56245-60-4
Product Name(2S,3R,4S,5R,6R)-2-(Ethylthio)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
IUPAC Name(2S,3R,4S,5R,6R)-2-ethylsulfanyl-6-(hydroxymethyl)oxane-3,4,5-triol
Molecular FormulaC8H16O5S
Molecular Weight224.28 g/mol
SynonymsEthyl 1-Thio-β-D-galactopyranoside; Ethyl 1-Deoxy-1-thio-β-D-galactopyranoside;
Isomeric SMILESCCS[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)O


Product name: Ethyl thio-β-D-galactoside

CAS: 56245-60-4             F.M.: C8H16O5S                      F.W.: 224.28





White crystalline power



Readily soluble in water

and almost insoluble in ether


Appearance of solution

Dissolve 0.5 gin 10 ml of water,

and the solution should be clear


MS and NMR

Should comply



IR and TLC


Melting point

110 - 125 °C

120 - 122 °C

Loss Weight On Dryness

Max. 1%


Residue on ignition

Max. 1%


Heavy metals




Max. 1%


Assay by HPLC

Min. 98%



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