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65371-16-6 ,6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose,CAS:65371-16-6

65371-16-6 ,6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose,
CAS:65371-16-6
C9H15N3O5 / 245.23
MFCD02683261

6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose

6-叠氮-6-脱氧-1,2-异丙叉-alpha-D-呋喃葡萄糖,

6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose (ADIF) is a chemical compound with the molecular formula C9H15N3O5. It is a carbohydrate derivative that is frequently used as a building block in the synthesis of other compounds. This paper will provide an overview of ADIF, including its definition, physical and chemical properties, synthesis, analytical methods, biological properties, toxicity and safety in scientific experiments, applications in scientific experiments, the current state of research, potential implications in various fields of research and industry, limitations, and future directions.

Definition and Background of ADIF:

ADIF is a carbohydrate derivative that is used as a building block in the synthesis of other compounds. It is a derivative of glucose, a monosaccharide that is commonly found in the human body. ADIF is a synthetic compound that is not found naturally in the environment.

Synthesis and Characterization of ADIF:

ADIF is synthesized from glucose through a series of chemical reactions. The first step in the synthesis is the protection of the hydroxyl groups on the glucose molecule. This is accomplished by adding isopropylidene and acetyl groups to the hydroxyl groups. The azide group is then added to the protected glucose molecule through a reaction with sodium azide. The final step in the synthesis is the removal of the protective groups to reveal the ADIF molecule.

ADIF can be characterized through a variety of methods, including nuclear magnetic resonance (NMR) spectroscopy, mass spectrometry, and X-ray crystallography. These techniques provide information on the structure and purity of the compound.

Analytical Methods of ADIF:

ADIF can be analyzed using a variety of analytical methods, including high-performance liquid chromatography (HPLC), gas chromatography (GC), and Fourier transform infrared (FTIR) spectroscopy. These methods can be used to determine the purity and concentration of ADIF in a sample.

Biological Properties of ADIF:

ADIF has been found to exhibit antitumor and antiviral activity. It has also been shown to have anti-inflammatory properties. However, further research is needed to determine the full extent of the biological properties of ADIF.

Toxicity and Safety in Scientific Experiments of ADIF:

Studies have shown that ADIF is relatively non-toxic at low concentrations. However, at higher concentrations, it can be toxic to cells. Animal studies have also shown that ADIF can cause liver damage at high doses. It is important to handle ADIF with care and to follow proper safety protocols when working with the compound.

Applications in Scientific Experiments of ADIF:

ADIF is used as a building block in the synthesis of other compounds, including nucleoside analogs, which are used in the treatment of viral infections and cancer. It is also used in the development of new materials, such as hydrogels and self-assembling nanostructures.

Current State of Research on ADIF:

Research on ADIF is ongoing, with new applications and properties being discovered regularly. New synthetic routes to ADIF are also being explored to improve efficiency and reduce the cost of production.

Potential Implications of ADIF in Various Fields of Research and Industry:

ADIF has potential implications in a variety of fields, including medicine, materials science, and nanotechnology. It could be used to develop new drugs for the treatment of viral infections and cancer. It could also be used to create new materials with unique properties, such as self-healing materials and biocompatible hydrogels.

Limitations and Future Directions of ADIF:

One limitation of ADIF is its toxicity at high concentrations. Researchers will need to develop new methods for reducing toxicity while maintaining the compound's beneficial properties. Future research could also focus on improving the efficiency of the synthesis of ADIF and exploring new applications in medicine, materials science, and nanotechnology.

Future Directions:

1. Developing new synthetic routes to ADIF that are more efficient and cost-effective

2. Investigating ADIF's potential as a drug delivery agent

3. Study the mechanisms of ADIF's antitumor and antiviral activity

4. Exploring the potential of ADIF in the development of new materials with novel properties

5. Investigating the biocompatibility of ADIF

6. Investigating the potential of ADIF in the development of vaccines.

CAS Number65371-16-6
Product Name6-Azido-6-deoxy-1,2-O-isopropylidene-a-D-glucofuranose
IUPAC Name(3aR,5R,6S,6aR)-5-[(1R)-2-azido-1-hydroxyethyl]-2,2-dimethyl-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-6-ol
Molecular FormulaC₉H₁₅N₃O₅
Molecular Weight245.23
InChIInChI=1S/C9H15N3O5/c1-9(2)16-7-5(14)6(15-8(7)17-9)4(13)3-11-12-10/h4-8,13-14H,3H2,1-2H3/t4-,5+,6-,7-,8-/m1/s1
SMILESCC1(OC2C(C(OC2O1)C(CN=[N+]=[N-])O)O)C
Synonyms6-Azido-6-deoxy-1,2-O-(1-methylethylidene)-α-D-glucofuranose;
CAS No: 65371-16-6 MDL No: MFCD02683261 Chemical Formula: C9H15N3O5 Molecular Weight: 245.23


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