1000890-36-7 , 2-O-(4-Nitrophenyl)-a-D-N-glycolylneuraminic acid

1000890-36-7 , 2-O-(4-Nitrophenyl)-a-D-N-glycolylneuraminic acid
C17H22N2O12 / 446.36
MFCD04039648

2-O-(4-Nitrophenyl)-a-D-N-glycolylneuraminic acid

2-O-(4-Nitrophenyl)-a-D-N-glycolylneuraminic acid is commonly used to measure the activity of sialidase enzymes, specifically those that cleave glycoconjugates containing 2-O-(4-nitrophenyl)-alpha-D-N-glycolylneuraminic acid. The resulting product can be detected by measuring the absorbance at a specific wavelength using a spectrophotometer. This substrate offers a high degree of specificity for glycolylneuraminic acid-containing substrates and is useful for both research and diagnostic purposes.

CAS Number	1000890-36-7
Product Name	2-O-(4-Nitrophenyl)-alpha-D-N-glycolylneuraminic acid
IUPAC Name	(2S,4S,5R,6R)-4-hydroxy-5-[(2-hydroxyacetyl)amino]-2-(4-nitrophenoxy)-6-[(1R,2R)-1,2,3-trihydroxypropyl]oxane-2-carboxylic acid
Molecular Formula	C17H22N2O12
Molecular Weight	446.365
InChI	InChI=1S/C17H22N2O12/c20-6-11(23)14(25)15-13(18-12(24)7-21)10(22)5-17(31-15,16(26)27)30-9-3-1-8(2-4-9)19(28)29/h1-4,10-11,13-15,20-23,25H,5-7H2,(H,18,24)(H,26,27)/t10-,11+,13+,14+,15+,17+/m0/s1
InChI Key	XZIZFIVNPXSZFF-ZLVOJWICSA-N
SMILES	C1C(C(C(OC1(C(=O)O)OC2=CC=C(C=C2)[N+](=O)[O-])C(C(CO)O)O)NC(=O)CO)O
Synonyms	Glycoylyl5Ac2-α-PNP; N-(2-Hydroxyacetyl)-2-O-(4-nitrophenyl)-α-neuraminic Acid;