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  • 137629-36-8 ,2-Nitrophenyl b-D-glucuronide,CAS:137629-36-8
137629-36-8 ,2-Nitrophenyl b-D-glucuronide,CAS:137629-36-8

137629-36-8 ,2-Nitrophenyl b-D-glucuronide,CAS:137629-36-8

137629-36-8 ,2-Nitrophenyl b-D-glucuronide,
CAS:137629-36-8
C12H13NO9 / 315.23
MFCD00152148

2-Nitrophenyl b-D-glucuronide

2-Nitrophenyl-b-D-glucuronide is a chromogenic substrate used to detect the activity of beta-glucuronidase in various biological samples. Upon hydrolysis by the enzyme, the substrate releases 2-nitrophenol, which can be spectrophotometrically measured at 405 nm. The substrate is commonly used in clinical assays to evaluate liver and kidney function, as well as in drug metabolism studies. It is also used in environmental monitoring to assess the presence of microbial activity in soil and water samples. Overall, 2-Nitrophenyl-b-D-glucuronide is a widely used substrate with excellent sensitivity and specificity, making it a valuable tool in enzymology research and diagnostic testing.

CAS Number137629-36-8
Product Name(2S,3S,4S,5R,6S)-3,4,5-Trihydroxy-6-(2-nitrophenoxy)tetrahydro-2H-pyran-2-carboxylic acid
IUPAC Name(2S,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(2-nitrophenoxy)oxane-2-carboxylic acid
Molecular FormulaC12H13NO9
Molecular Weight315.23 g/mol
InChIInChI=1S/C12H13NO9/c14-7-8(15)10(11(17)18)22-12(9(7)16)21-6-4-2-1-3-5(6)13(19)20/h1-4,7-10,12,14-16H,(H,17,18)/t7-,8-,9+,10-,12+/m0/s1
InChI KeyUADVJQJTJSOJOQ-GOVZDWNOSA-N
SMILESC1=CC=C(C(=C1)[N+](=O)[O-])OC2C(C(C(C(O2)C(=O)O)O)O)O
Synonyms2-Nitrophenyl β-D-Glucopyranosiduronic Acid;
Canonical SMILESC1=CC=C(C(=C1)[N+](=O)[O-])OC2C(C(C(C(O2)C(=O)O)O)O)O
Isomeric SMILESC1=CC=C(C(=C1)[N+](=O)[O-])O[C@H]2[C@@H]([C@H]([C@@H]([C@H](O2)C(=O)O)O)O)O

CAS No: 137629-36-8 Synonyms: ONP-GlcA MDL No: MFCD00152148  Chemical Formula: C12H13NO9 Molecular Weight: 315.23

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