欢迎光临~北京凯森莱科技有限公司
语言选择: 中文版 ∷  英文版
  • 50-69-1, D-核糖, D-Ribose, Cas: 50-69-1
50-69-1, D-核糖, D-Ribose, Cas: 50-69-1

50-69-1, D-核糖, D-Ribose, Cas: 50-69-1

50-69-1,D-Ribose,
D-核糖,
Cas: 50-69-1
C5H10O5 / 150.13
MFCD00135453

D-核糖, D-Ribose

D-ribose (Rib) is an aldopentose, a component of RNA and a constituent of numerous cofactors, and certain vitamins. (Collins, 2006). Ribose is a component of bacterial polysaccharides found in Salmonella (Lindberg, 1990). Ribosylation leads to the production of significant amounts of advanced glycation end products, both extracellularly and intracellularly, it may be involved in cell dysfunction and subsequent cognitive impairments.

Title: D-Ribose

CAS Registry Number: 50-69-1

Molecular Formula: C5H10O5

Molecular Weight: 150.13

Percent Composition: C 40.00%, H 6.71%, O 53.29%

Literature References: Prepd by hydrolysis of yeast-nucleic acid: Levene, Jacobs, Ber. 42, 1201, 3247 (1909); Levene, Clark, J. Biol. Chem. 46, 19 (1921); Bredereck, Ber. 71, 408 (1938); Bredereck et al., ibid. 73, 956 (1940); Phelps, US 2152662 (1939 to U.S. Gov't); by ion-exchange resin chromatography: Cohn, Science 109, 377 (1949); J. Am. Chem. Soc. 71, 2275 (1949); 72, 1471 (1950). From glucose: Karrer, Helv. Chim. Acta 18, 1435 (1935); Austin, Humoller, J. Am. Chem. Soc. 56, 1152 (1934); Kuhn et al., Ber. 68, 1765 (1935); from nucleosides: Laufer, Charney, US 2379913US 2379914 (both 1945 to Schwarz Labs.); from D-erythrose: Sowden, J. Am. Chem. Soc. 72, 808 (1950); from L-glutamic acid: Koga et al., Tetrahedron Lett. 1971, 263. Reduction of D-ribonic acid: van Ekenstein, Blanksma, Chem. Zentralbl. 1913, II, 1562; Steiger, Helv. Chim. Acta 19, 189 (1936). Review: Overend, Stacey, in Nucleic Acids vol. I, E. Chargaff, J. N. Davidson, Eds. (Academic Press, New York, 1955) pp 1-80.

Properties: Plates from abs alcohol, mp 87°. Shows complex mutarotation: Phelps et al., J. Am. Chem. Soc. 56, 748 (1934). Final [a]D24 -25° (water). Sol in water, slightly sol in alc.

Melting point: mp 87°

Optical Rotation: [a]D24 -25° (water)

 

Derivative Type: Phenylosazone

Molecular Formula: C17H20N4O3

Molecular Weight: 328.37

Percent Composition: C 62.18%, H 6.14%, N 17.06%, O 14.62%

Properties: Yellow needles from pyridine + water, mp 163-164°.

Melting point: mp 163-164°

 

Derivative Type: Methyl-D-riboside

Properties: Crystals from ethyl acetate, mp 83-84°. [a]D20 -113.6° (p = 3), Minsaas, Ann. 512, 286 (1934).

Melting point: mp 83-84°

Optical Rotation: [a]D20 -113.6° (p = 3), Minsaas, Ann. 512, 286 (1934)

CAS Number50-69-1
Product Name(2R,3R,4R)-2,3,4,5-tetrahydroxypentanal
IUPAC Name(2R,3R,4R)-2,3,4,5-tetrahydroxypentanal
Molecular FormulaC5H10O2
Molecular Weight150.13 g/mol
InChIInChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m0/s1
InChI KeyPYMYPHUHKUWMLA-LMVFSUKVSA-N
SMILESO=C[C@@H]([C@@H]([C@@H](CO)O)O)O
SolubilitySoluble in DMSO
SynonymsD Ribose, D-Ribose, Ribose
Canonical SMILESC(C(C(C(C=O)O)O)O)O
Isomeric SMILESC([C@H]([C@H]([C@H](C=O)O)O)O)O


CAS No: 50-69-1 Synonyms: (2R,3R,4R)-2,3,4,5-Tetrahydroxypentanal MDL No: MFCD00135453 Chemical Formula: C5H10O5 Molecular Weight: 150.13
References: 1. Salerno C, D'Eufemia P, Finocchiaro R, Celli M, Spalice A, Iannetti P, Crifo C, Giardini O, Biochim. Biophys. Acta 1999, Jan 6, 1453(1), 135-402. Berezovskii VM, Rodionova EP, Chem. Abstr. 1955, Vol49, p6838


在线询价

用手机扫描二维码关闭
二维码