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  • 66170-10-3, 维生素C磷酸酯钠, L-抗坏血酸-2-磷酸三钠盐, Sodium L-ascorbyl-2-phosphate, CAS:66170-10-3
66170-10-3, 维生素C磷酸酯钠, L-抗坏血酸-2-磷酸三钠盐, Sodium L-ascorbyl-2-phosphate, CAS:66170-10-3

66170-10-3, 维生素C磷酸酯钠, L-抗坏血酸-2-磷酸三钠盐, Sodium L-ascorbyl-2-phosphate, CAS:66170-10-3

66170-10-3, 维生素C磷酸酯钠,
L-抗坏血酸-2-磷酸三钠盐,
Sodium L-ascorbyl-2-phosphate,
CAS:66170-10-3
C6H6Na3O9P / 322.05

维生素C磷酸酯钠, L-抗坏血酸-2-磷酸三钠盐,

Sodium L-ascorbyl-2-phosphate

2-Phospho-L-Ascorbic acid trisodium salt is a form of vitamin C that has been shown to have biological activity in basic fibroblast cells. It also inhibits the production of phosphatase, which is an enzyme that breaks down collagen. 2-Phospho-L-Ascorbic acid trisodium salt has significant cytotoxicity and may be used as a treatment for cancer. This compound is also used in diagnosing diseases such as diabetes mellitus and Alzheimer's disease by measuring the concentration of dehydroascorbic acid in blood plasma or serum.

2-Phospho-L-ascorbic acid trisodium salt is a stable ascorbic acid derivative used in cell culture. In combination with FGF-2, it maintains differentiation potential in bone marrow-derived mesenchymal stem cells (MSC) through increased expression of HGF. L-Ascorbic acid 2-phosphate may be used in cell differentiation and tissue engineering applications. 2-Phospho-L-ascorbic acid trisodium salt also exhibits synergistic protection of hMSCs under oxidative stress in combination with N-acetylcysteine. Asc-2P is used in studies of gene repression, such as the repression of dihydrotestosterone-induced dickkopf-1 expression. AA2P has been shown to increase myogenin gene expression and promote differentiation in L6 muscle cells.

CAS Number66170-10-3
Product NameSodium ascorbyl phosphate
IUPAC Nametrisodium;[(2R)-2-[(1S)-1,2-dihydroxyethyl]-3-oxido-5-oxo-2H-furan-4-yl] phosphate
Molecular FormulaC6H6Na3O9P
Molecular Weight322.05 g/mol
InChIInChI=1S/C6H9O9P.3Na/c7-1-2(8)4-3(9)5(6(10)14-4)15-16(11,12)13;;;/h2,4,7-9H,1H2,(H2,11,12,13);;;/q;3*+1/p-3/t2-,4+;;;/m0.../s1
InChI KeyVWCFDYSMDMCPLU-OFBPEYICSA-K
SMILESC(C(C1C(=C(C(=O)O1)OP(=O)([O-])[O-])[O-])O)O.[Na+].[Na+].[Na+]
SolubilitySoluble in DMSO, not in water
Synonyms2-phosphoascorbate, AA-2P cpd, Asc-2-O-phosphate, Asc2P cpd, ascorbate-2-phosphate, ascorbic acid 2-phosphate, ascorbyl-2-monophosphate, ascorbyl-2-phosphate, L-ascorbic acid 2-phosphate, magnesium ascorbate-2-phosphate, magnesium-L-ascorbyl-2-phosphate, sodium ascorbyl phosphate
Canonical SMILESC(C(C1C(=C(C(=O)O1)OP(=O)([O-])[O-])[O-])O)O.[Na+].[Na+].[Na+]
Isomeric SMILESC([C@@H]([C@@H]1C(=C(C(=O)O1)OP(=O)([O-])[O-])[O-])O)O.[Na+].[Na+].[Na+]


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