66215-27-8, 灭蝇胺, Cyromazine, Cas:66215-27-8

66215-27-8, 灭蝇胺,
Cyromazine,
Cas:66215-27-8
MFCD00078650
C6H10N6 / 166.18

灭蝇胺, Cyromazine,

Cyromazine is a pesticide that belongs to the family of organophosphates. It inhibits the ryanodine receptor, which leads to muscle paralysis and death. Cyromazine has been shown to have insecticidal activity against various species of insects. The toxicity of cyromazine is studied by exposing mammalian cells in culture to various concentrations of this compound. The reaction solution was analyzed using an analytical method involving colloidal gold and cell nuclei. Cyromazine can be detected with a fluorescence probe and the toxicity studies are conducted on human serum samples. Experimental solubility data for cyromazine in anhydrous sodium chloride is available from various sources.

Title: Cyromazine

CAS Registry Number: 66215-27-8

CAS Name: N-Cyclopropyl-1,3,5-triazine-2,4,6-triamine

Additional Names: 2-cyclopropylamino-4,6-diamino-s-triazine

Manufacturers' Codes: CGA-72662

Trademarks: Larvadex (Novartis); Neporex (Novartis); Trigard (Syngenta); Vetrazin (Novartis)

Molecular Formula: C6H10N6

Molecular Weight: 166.18

Percent Composition: C 43.37%, H 6.07%, N 50.57%

Literature References: Insect growth regulator. Prepn: H. U. Brechbuhler et al., DE 2736876; eidem, US 4225598 (1978, 1980 to Ciba-Geigy). Activity: R. D. Hall, M. C. Foehse, J. Econ. Entomol. 73, 564 (1980); R. J. Hart et al., Aust. Vet. J. 59, 104 (1982).

Properties: Crystals, mp 219-222°.

Melting point: mp 219-222°

Use: Insecticide.

Therap-Cat-Vet: Ectoparasiticide.

CAS Number	66215-27-8
Product Name	Cyromazine
IUPAC Name	2-N-cyclopropyl-1,3,5-triazine-2,4,6-triamine
Molecular Formula	C6H10N6
Molecular Weight	166.18 g/mol
InChI	InChI=1S/C6H10N6/c7-4-10-5(8)12-6(11-4)9-3-1-2-3/h3H,1-2H2,(H5,7,8,9,10,11,12)
InChI Key	LVQDKIWDGQRHTE-UHFFFAOYSA-N
SMILES	C1CC1NC2=NC(=NC(=N2)N)N
Solubility	All in g/kg, 20 °C: In methanol 22, isopropanol, 2.5, acetone, 1.7, n-octanol 1.2, dichloromethane 0.25, toluene, 0.015, hexane 0.0002 In water, 1.30X10+4 mg/L at 25 °C, pH 7.1 In water, 1.1% at 20 °C (pH 7.5); methanol 1.7%
Synonyms	2-cyclopropylamino-4,6-diamino-s-triazine, CGA 72662, CGA-72662, cyromazin, cyromazine, cyromazine dihydrochloride, Larvadex, N-cyclopropyl-1,3,5-triazine-2,4,6-triamine, N-cyclopropylmelamine, Neporex, Vetrazin
Canonical SMILES	C1CC1NC2=NC(=NC(=N2)N)N