Nonanoyl-N-Hydroxyethylglucamide,HEGA-9

1-脱氧-1-[(2-羟基乙基)(1-氧代壬基)氨基]-D-山梨糖醇,

Nonanoyl-N-hydroxyethylglucamide, also known as n-octanoyl-N-decyl-N-methylglucamide, is a nonionic surfactant that is extensively used in various fields of research and industry. It is a biodegradable and environmentally friendly compound that is commonly used as a detergent, emulsifier, and solubilizing agent.

Synthesis and Characterization

Nonanoyl-N-hydroxyethylglucamide is synthesized by the reaction of decylamine and 1-octanoyl-2,3,4,6-tetra-O-acetyl-beta-D-glucopyranoside in the presence of trifluoroacetic acid. The product is purified and characterized using various spectroscopic techniques such as infrared, nuclear magnetic resonance, and mass spectroscopy.

Analytical Methods

Nonanoyl-N-hydroxyethylglucamide can be analyzed using various analytical methods such as high-performance liquid chromatography, gas chromatography, and capillary electrophoresis. These methods provide accurate and reliable results for the quantification and identification of the compound in various matrices.

Biological Properties

Nonanoyl-N-hydroxyethylglucamide has been shown to have antimicrobial, anti-inflammatory, and anticancer properties. It has been reported to inhibit the growth of various bacteria and fungi, reduce the production of pro-inflammatory cytokines, and induce apoptosis in cancer cells.

Toxicity and Safety in Scientific Experiments

Nonanoyl-N-hydroxyethylglucamide is considered safe and non-toxic in scientific experiments. It has been tested for acute oral toxicity, skin irritation, and eye irritation and found to be non-irritating and non-sensitizing. However, prolonged exposure to the compound may cause skin and eye irritation.

Applications in Scientific Experiments

Nonanoyl-N-hydroxyethylglucamide has numerous applications in scientific experiments such as in the extraction and purification of proteins, DNA, and RNA, and in the solubilization and stabilization of membrane proteins. It is also used as a detergent in microfluidic devices, chromatography, and electrophoresis.

Current State of Research

Nonanoyl-N-hydroxyethylglucamide is an active area of research, and new applications for the compound are constantly being discovered. Recent research has focused on the development of novel analytical methods for the quantification and identification of the compound in various matrices.

Potential Implications in Various Fields of Research and Industry

Nonanoyl-N-hydroxyethylglucamide has potential implications in various fields of research and industry such as in biotechnology, pharmaceuticals, and nanotechnology. The compound has excellent biocompatibility and biodegradability, making it a suitable candidate for drug delivery systems, biomaterials, and tissue engineering.

Limitations and Future Directions

Despite the numerous applications of Nonanoyl-N-hydroxyethylglucamide, there are still limitations and future directions that need to be addressed. Some of these limitations include the limited solubility of the compound in non-polar solvents, and the need to develop more efficient methods for the synthesis and purification of the compound.

Conclusion

Nonanoyl-N-hydroxyethylglucamide is a versatile compound that has numerous applications in various fields of research and industry. Its excellent biocompatibility, biodegradability, and low toxicity make it a suitable candidate for a variety of applications. Further research is needed to overcome the limitations and explore the full potential of this compound in various fields.