2636-92-2, 2-脱氧-2-氨基-D-甘露糖, D-甘露糖胺,2-Amino-2-Deoxymannose, CAS:2636-92-2

2636-92-2 , 2-脱氧-2-氨基-D-甘露糖,
D-甘露糖胺,
2-Amino-2-Deoxymannose,
CAS:2636-92-2
C6H13NO5 / 179.17

2-脱氧-2-氨基-D-甘露糖，D-甘露糖胺, 2-Amino-2-Deoxymannose

Mannosamine (Man, 2-Amino-2-Deoxymannose) has the axial hydroxyl group at position 2 replaced by an amino group (Collins, 2006). Mannosamine has importance in the biosynthesis of sialic acids as they are synthesized by the condensation of D-mannosamine with pyruvic acid. Mannosamine has been found to have antitumor activity on human leukemia T-cell lines (Onoda, 1985). Mannosamine was also reported to inhibit glycosylphosphatidylinositol (GPI) synthesis in trypanosomes (Eckert, 1999).

CAS Number	2636-92-2
Product Name	2-Amino-2-deoxymannose
IUPAC Name	(2S,3R,4S,5R)-2-amino-3,4,5,6-tetrahydroxyhexanal
Molecular Formula	C6H13NO5
Molecular Weight	179.17 g/mol
InChI	InChI=1S/C6H13NO5/c7-3(1-8)5(11)6(12)4(10)2-9/h1,3-6,9-12H,2,7H2/t3-,4-,5-,6-/m1/s1
InChI Key	FZHXIRIBWMQPQF-KVTDHHQDSA-N
SMILES	C(C(C(C(C(C=O)N)O)O)O)O
Synonyms	2-amino-2-deoxymannose, D-mannosamine, mannosamine, mannosamine hydrochloride, (D)-isomer, mannosamine, (D)-isomer
Canonical SMILES	C(C(C(C(C(C=O)N)O)O)O)O
Isomeric SMILES	C([C@H]([C@H]([C@@H]([C@@H](C=O)N)O)O)O)O